jsPedigrees

Updated 9-March-2018 Instructions

1. Click members of the pedigree and an Edit menu will pop up that allows you to:
• Add members of the pedigree related to the selected person
• Change the sex or disease status of the selected person
• Delete the selected person
2. The Edit menu allows un-doing and re-doing changes.
3. Click "solve" to solve the pedigree (note that this can take a long time if the peidgree is large).
1. The solution will appear in the box below the "solve" button.
2. The solution will list the 4 possible modes of inheritance
3. • If the mode is possible, it will list genotypes for each individual that are consistent with the pedigree and the mode. Symbols can be found in the tables below.
   • If the mode is not possible, it will say "Not possible".

Solve
Autosomal Recessive Genotype Phenotype A A Normal A a Normal a a Affected	Autosomal Dominant Genotype Phenotype B B Affected B b Affected b b Normal
Sex-linked Recessive Genotype Phenotype XD XD Normal Female XD Xd Normal Female Xd Xd Affected Female XD Y Normal Male Xd Y Affected Male	Sex-linked Dominant Genotype Phenotype XE XE Affected Female XE Xe Affected Female Xe Xe Normal Female XE Y Affected Male Xe Y Normal Male